Description
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🔬 Science & Mechanism
Selank is a synthetic heptapeptide analog of tuftsin, developed in Russia as an anxiolytic nootropic. It is believed to:
- Modulate the GABAergic system, supporting calm without sedation.
- Enhance serotonin metabolism, promoting mood stability.
- Provide neuroprotective and cognitive support under stress.
📊 Clinical Evidence
- Russian trials suggest reduced anxiety and improved cognitive performance under stress.
- Demonstrated benefits in generalized anxiety disorder (GAD) and stress-induced fatigue.
- Anecdotally popular among biohackers for presentations, high-pressure work, and public speaking.
💉 Dosing Guide (Educational)
Reported Protocols:
- 250–500 mcg, 1–2× daily, AM or pre-stress situations.
- Cycles of 2–8 weeks, often stacked with Semax.
💧 Reconstitution (10 mg vial + 2 mL BAC water)
- Final concentration = 5 mg/mL
- On insulin syringe (100 units = 1 mL): 50 mcg per unit
| Desired Dose | Volume (mL) | Syringe Units |
| 250 mcg | 0.05 mL | 5 units |
| 500 mcg | 0.10 mL | 10 units |
| 1,000 mcg (1 mg) | 0.20 mL | 20 units |
🧊 Storage
- Refrigerate lyophilized vial (2–8 °C).
- After reconstitution, refrigerate and use within 30 days.
- Protect from light.
❓ FAQ
How does Selank feel compared to Semax?
Selank has a calming, anxiolytic profile, while Semax is more stimulating for focus. Many stack them for balanced “calm clarity.”
Is Selank sedating?
No—it is typically calming without drowsiness.
When should I take it?
Before stressful events, public speaking, or daily during high-stress cycles.
⚠️ Disclaimer
- For educational purposes only.
- Not FDA or Health Canada approved for medical use.
- Customers assume responsibility for safe handling.
📚 References
- Medvedev AE, et al. Neuropeptide Selank: a novel anxiolytic and nootropic agent. Physiol Behav. 2018.
🔗 https://pubmed.ncbi.nlm.nih.gov/29653214/ - Andreeva LA, et al. Clinical study of Selank in anxiety disorders. Zh Nevrol Psikhiatr Im S S Korsakova. 2005.
🔗 https://pubmed.ncbi.nlm.nih.gov/15847314/ - Ashmarin IP, et al. Mechanisms of Selank anxiolytic action: GABAergic modulation. Neurosci Behav Physiol. 2007.
🔗 https://pubmed.ncbi.nlm.nih.gov/17608771/ - Dolotov OV, et al. Selank and serotonin metabolism: effects on tryptophan hydroxylase. Bull Exp Biol Med. 2011.
🔗 https://pubmed.ncbi.nlm.nih.gov/22183792/





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