MOTS-c (Mitochondrial Peptide) 5 mg / 10 mg Vial

Description

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🔬 Science & Mechanism

MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a mitochondrial-derived peptide (16 amino acids) that regulates metabolism and stress response.

• Activates AMPK and increases insulin sensitivity.
• Enhances fatty acid oxidation and mitochondrial efficiency.
• Plays a role in exercise performance and adaptive stress response.

📊 Clinical Evidence

• Animal studies show MOTS-c improves glucose tolerance and reverses diet-induced obesity.
• In humans, MOTS-c increases with exercise and is linked to metabolic health and endurance.
• Early research suggests potential for healthy aging and resilience under cellular stress.

💉 Dosing Guide (Educational)

Reported Protocols:

• 5–10 mg per week, split into 2–3 doses.
• Typically administered subcutaneously (abdomen, thigh).
• Cycled in 4–8 week blocks.

💧 Reconstitution (10 mg vial + 2 mL BAC water)

• Final concentration = 5 mg/mL
• On insulin syringe (100 units = 1 mL): 50 mcg per unit

🧊 Storage

• Store lyophilized vial refrigerated (2–8 °C).
• After reconstitution, refrigerate and use within 30 days.
• Protect from light.

❓ FAQ

Is MOTS-c a longevity peptide?

Yes—early research suggests MOTS-c helps cells adapt to stress and supports longevity pathways via AMPK activation.

Does it stack with NAD⁺?

Yes—NAD⁺ + MOTS-c is a popular mitochondrial optimization stack, often paired with CoQ10.

Can it help with exercise performance?

Animal and early human studies show improved endurance and energy metabolism.

⚠️ Disclaimer

• For educational purposes only.
• Not FDA or Health Canada approved for medical use.
• Customers assume responsibility for safe handling.

📚 References

1. Lee C, et al. MOTS-c: A novel mitochondrial-derived peptide regulating muscle and metabolism. Cell Metab. 2015.
   🔗 https://pubmed.ncbi.nlm.nih.gov/25738459/
2. Reynolds JC, et al. MOTS-c increases with exercise and regulates metabolic homeostasis. Nat Commun. 2021.
   🔗 https://pubmed.ncbi.nlm.nih.gov/33414478/
3. Zarse K, et al. Mitochondrial peptides and their roles in aging and metabolism. Trends Endocrinol Metab. 2019.
   🔗 https://pubmed.ncbi.nlm.nih.gov/31155308/